The 1918 Pandemic's Death-by-Age Curve Closely Tracks the Peaks and Valleys of H3 Antibodies (IMAGE)

University of Arizona

The 1918 Pandemic's Death-by-Age Curve Closely Tracks the Peaks and Valleys of H3 Antibodies

Caption

The researchers found a remarkable overlap between death rates in various age groups in 1918 and childhood exposure to an H3 influenza virus mismatched in its major antigenic protein to the H1 virus of 1918: age groups with the highest percentage of individuals exhibiting H3 antibodies fared the worst in 1918, and the death-by-age curve closely tracks the peaks and valleys of H3 antibodies in cohorts born before, during and after the 1889 H3 pandemic.

Credit

Michael Worobey

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