Schematic Representation of the Study (IMAGE)

Institute for Basic Science

Schematic Representation of the Study

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A tailored amount of zirconium ions (Zr4+) in the 7CZ nanoparticles (7CZ NP) boost their performance as antioxidants: they are more efficient in converting Ce4+ into Ce3+ compared with the traditional ceria nanoparticles (Ceria NP), therefore a smaller dose suffice. After sepsis was induced in rats and mice with a puncture in the cecum (CLP), injection of 7CZ nanoparticles resulted in an increase in survival rate and a decrease in organ injuries.

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