Inhibition of ZFP541 gene function by genome editing in mice (IMAGE)

Kumamoto University

Inhibition of ZFP541 gene function by genome editing in mice

Caption

When the function of the ZFP541 gene in mice is eliminated by genome editing, male germ cells initiate meiosis but die in the process, thus becoming infertile because they cannot produce sperm.

Credit

Fig. 2c (top) & 2d (WT & Zfp541 KO) from (Horisawa-Takada, Y. et. al., Nature Communications, 2021) under CC BY 4.0 / Edited: These images are smaller parts of the original image.

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