Stockpiling Antibiotic Synbodies (IMAGE)
Caption
Synbodies are selected on peptide chips containing a premade set of 10,000 peptides placed in neat rows on a microscope glass slide, called a microarray. To generate a synbody with antibiotic activity, a solution containing bacteria or viruses can be placed on the microarray. To save time, the group performed a pre-screen of a large number of pathogens on the microarray and found 100 peptides that would be diverse enough so that any pathogen screened would bind to two or more peptides.
Credit
Biodesign Institute, Arizona State University
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