Schematic Illustrations (IMAGE)
Caption
The green oval indicates a neuron while the orange oval with a protruding fiber, radial glia. Neurons are thought to translocate themselves to the cerebral cortex. Left: In the developing brain of normal ferret, neurons translocate themselves to the cerebral cortex along the radial glial fiber. Right: In the developing brain of TD ferret, some neurons cannot reach the cerebral cortex due to aberrant radial glial fibers, but stay deep in the cerebrum to form clusters of neurons, i.e., PNH.
Credit
Kanazawa University
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