Gray Matter Volumes Vary By Psychosis Biotypes (IMAGE)
Caption
MRI scans showed that people with psychosis had different patterns of reduced gray matter -- neurons and their connections, the brain's working tissue (orange/yellow) -- depending on their biotype. Derived from clusters of other biomarkers, the biotypes identify distinct subgroups of psychosis, likely involving different illness processes operating via different pathways. The scans helped to validate the distinctiveness of the biotypes. First-degree relatives showed similar, but reduced, patterns of biomarkers compared to their affected family members, suggesting that such features as lower-than-normal gray matter volume may be risk factors for psychosis.
Credit
Brett Clementz, Ph.D., University of Georgia
Usage Restrictions
None
License
Licensed content