Biotypes Group Psychosis Cases Into Distinct Clusters (IMAGE)

NIH/National Institute of Mental Health

Biotypes Group Psychosis Cases Into Distinct Clusters

Caption

LEFT: Psychosis cases with Biotype1 (red), Biotype2 (blue), Biotype3 (green) cluster distinctly when graphed by biomarker constructs. The gray cross/ellipse represents the biomarker profile of healthy controls, who scored similarly to Biotype 3 cases on measures of Cognitive Control. RIGHT: Psychosis cases similarly graphed by biomarker constructs show much less distinct clusters when grouped by the traditional diagnostic categories schizophrenia (sz), schizoaffective disorder (SZaff), and bipolar disorder with psychosis (BDP).

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Brett Clementz, Ph.D., University of Georgia

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