XPD Domains (IMAGE)

DOE/Lawrence Berkeley National Laboratory

XPD Domains

Caption

The four domains of XPD: the helicases HD2 (green) and HD1 (blue), the iron-sulfur complex 4FeS (rust), and the Arch (purple). Sites of mutations that cause xeroderma pigmentosum are shown in red, those causing both xeroderma pigmentosum and Cockayne syndrome in gold, and those of trichothiodystrophy in purple. A strand of unwound DNA is shown passing under the arch.

Credit

Lawrence Berkeley National Laboratory

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