Fig. 2 (IMAGE) Osaka University Caption (a) Optical microscopy image of a mouse brain tissue section. (b,c) Mass spectrometry imaging of two regions of the optical microscopy image in positive ion mode and negative ion mode, respectively. (d,e) Score plots obtained by principal component analysis of mass spectra included in the selected regions in (b) and (c), respectively. (f,g) Intra-tissue distribution of the score values of the second and third principal components obtained by principal component analysis. We obtained feature images from differences in the structure of the brain tissue. Credit Reproduced with permission. Copyright (2021) American Chemical Society. https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04144 Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.