Mitochondria Meltdown Pummels Cell Nuclei (IMAGE) University of Pittsburgh Caption Reactive oxygen species pumped out by damaged mitochondria cause cell nuclei (blue) to oxidize (yellow) and shrivel. Credit Qian et al. (2019), PNAS. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.