減数分裂組換えの時に起こるDNA損傷修復のメカニズム (IMAGE)

Kumamoto University

減数分裂組換えの時に起こるDNA損傷修復のメカニズム

Caption

通常、減数分裂組換えの最初の段階でDNA切断が起こる。こうしたDNA切断は細胞にとって諸刃の剣であり、直ちに修復される必要がある。今回新たに同定されたC19ORF57遺伝子は、DNA損傷部位へBRCA2を呼び寄せる役割を果たす。

Credit

Dr. Kei-ichiro Ishiguro

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