High-Strength MRI Tracks MS Progression (IMAGE) Radiological Society of North America Caption Spatial distribution of vertex-wise frequency of intracortical and leukocortical lesions in 31 patients with multiple sclerosis at baseline and at follow-up. The lesion frequency is displayed for every voxel in the color overlay on 'fsaverage.' The number of patients showing cortical lesions in a particular voxel is specified by the bar. Maximum overlap (arrows) corresponds to lesions in 10 percent (three of 31) of patients. Despite the scattered distribution, cortical lesions are mainly confined within cortical sulci (shown as dark gray areas) while cortical gyri (shown as light gray areas) are less involved. Credit Radiological Society of North America Usage Restrictions May use with credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.