Clinical Features of FOP (IMAGE) University of Pennsylvania School of Medicine Caption Characteristic clinical features of fibrodysplasia ossificans progressiva (FOP). (A) Extra-skeletal bone formation in a three-dimensional reconstructed computed tomography scan of a 12-year-old child. (B) Radiograph of the feet of a 3-year-old child showing the symmetrical great toe malformations. Credit Credit: Eileen Shore, PhD and Frederick Kaplan, MD, University of Pennsylvania School of Medicine; Nature Genetics, 23 April 2006, DOI: 10.1038/ng1783 Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.