(IMAGE)

Tokyo University of Agriculture and Technology

Caption

TLR3 signaling activated by ds RNA [poly(I:C)] analogue induces the PGE2-mediated expression of RANKL that stimulates osteoclast formation and directly prolongs the life span of mature osteoclasts, that was leading alveolar bone resorption in periodontal disease.

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Masaki Inada, Tokyo University of Agriculture and Technology

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