Figure 2. Structural modeling of the WW-like autoinhibitory domain on USP8 (IMAGE)

Tokyo Institute of Technology

Figure 2. Structural modeling of the WW-like autoinhibitory domain on USP8

Caption

Researchers from Tokyo Tech have identified a WW-like autoinhibitory domain in USP8. The WW-like domain (blue) appears to occupy the ubiquitin-binding pocket of the catalytic domain (green), to facilitate enzymatic inhibition.

Credit

Communications Biology

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CC BY-NC

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