Figure 1 Mechanism underlying innate immune activation by CpG DNA and CXCL14. (IMAGE)

Tokyo Metropolitan Institute of Medical Science

Figure 1 Mechanism underlying innate immune activation by CpG DNA and CXCL14.

Caption

CXCL14 has binding domains for both CpG DNA and a cell surface receptor. The CpG DNA/CXCL14 complex is endocytosed by dendritic cells to activate the CpG DNA receptor Toll-like receptor 9 (TLR9).

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