ケトン体合成不全マウスは生後早期に脂肪肝を呈する (IMAGE)
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HMG-CoA Synthase 2(HMGCS2)の遺伝子を欠損させたケトン体合成不全マウス(下段)では、新生仔期より著しい脂肪肝になる。
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Dr. Yuichiro Arima
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(Fig. 3d) Reprinted by permission from Springer Nature Customer Service Centre GmbH: Springer Nature, Nature Metabolism, <a href="https://www.nature.com/articles/s42255-021-00342-6" target="_blank">Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation, Yuichiro Arima et. al., 18 February 2021</a> (2021) DOI: 10.1038/s42255-021-00342-6
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