Graphical abstract (IMAGE)

Kyoto University

Graphical abstract

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We show that we have succeeded in reproducing the entire differentiation process of male germ cells from mouse pluripotent stem cells in vitro.Top: scheme for male germ-cell development in mice. Bottom: scheme for the in vitro reconstitution of male germ-cell development by pluripotent stem cells. E, embryonic day; P, postnatal day.

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Provided by Yukiko Ishikura, a postdoctoral researcher at ASHBi Kyoto University

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