usher_siSANS_siCTRL (IMAGE) Johannes Gutenberg Universitaet Mainz Caption In the absence or dysregulation of SANS (siSANS), in contrast to a control (siCTRL), tri-snRNA complexes are not released from the Cajal bodies (coilin, red) but rather accumulate there (tri-snRNA component PRPF31, green). Credit ill./©: Uwe Wolfrum, Adem Yildirim Usage Restrictions This image may only be used in connection with the press release "Remarkable new insights into the pathology of Usher syndrome", issued by Johannes Gutenberg University Mainz on July 12, 2021. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.