Diabetes in Elderly, Lean Animals has a Different Cause from Obesity-Sssociated Type 2 Diabetes (IMAGE)

Salk Institute

Diabetes in Elderly, Lean Animals has a Different Cause from Obesity-Sssociated Type 2 Diabetes

Caption

Salk researchers show that diabetes in elderly, lean animals is caused by an overabundance of immune cells in fat. In this graphic, fat tissue is shown with representations of the immune cells called Tregs (orange). In aged mice with diabetes (represented on the right), Tregs are overexpressed in fat tissue and trigger insulin resistance. When Tregs are blocked, the fat cells in mice become insulin sensitive again.

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Salk Institute

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