Tomosynthesis Outperforms Digital Mammography in Five-Year Study (IMAGE)
Caption
Images in a 49-year-old woman with an advanced cancer diagnosed at screening digital breast tomosynthesis (DBT) after a negative two-dimensional digital mammogram (DM) 20 months prior. (a) Bilateral DM images obtained as part of DM/DBT study. The breasts are heterogeneously dense but no abnormality was detected. (b) Craniocaudal and mediolateral oblique images of right breast from slices of the DBT portion of the screening study demonstrate a poorly defined mass at the 12-o'clock site in the right breast (circle) on both views. (c) Targeted US scan shows a corresponding, irregular 2.4-cm solid mass at 12-o'clock in right breast. US-guided core biopsy yielded an invasive ductal carcinoma that was estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 negative (triple negative). (d) Maximum intensity projection image of right breast from contrast material-enhanced breast MRI. The large index lesion is visible as well as extensive satellites in the surrounding breast tissue. Mastectomy was performed, and additional sites of triple-negative cancer and ductal carcinoma in situ were found histologically. Axillary node dissection was negative.
Credit
Radiological Society of North America
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