Low-dose Chest CT Leaves DNA Intact (IMAGE)

Radiological Society of North America

Low-dose Chest CT Leaves DNA Intact

Caption

Peptide nucleic acid fluorescence in situ hybridization analysis performed to depict chromosome aberrations. Metaphase lymphocyte in an 87-year-old man obtained 15 minutes after standard-dose CT. Representative images of dicentric chromosomes with two centromeres (arrow) and of acentric fragments (arrowhead) are shown. The acentric fragments were created by the formation of dicentric chromosomes. (a) Chromosomal DNA. (b) Telomeres. (c) Centromeres. (d) Merged image. Blue = DNA, green = telomeres, red = centromeres.

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Radiological Society of North America

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