effects of painkiller Meclo (IMAGE) Institute of Science and Technology Austria Caption Within 30 minutes, the painkiller Meclo (meclofenamic acid) causes an aggregation of early endosomes - vesicles that form at the plasma membrane - in the root epidermis (magenta). This might explain the effect of NSAIDs on the trafficking of various plasma membrane-resident cargo proteins, including the PIN2 auxin transporter (green). © Shutang Tan / IST Austria Credit © Shutang Tan / IST Austria Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.