Hemophilia (2 of 2) (IMAGE) University of the Witwatersrand Caption Patients with hemophilia bleed spontaneously or following trauma. The most common sites of bleeding are into joints, but bleeds can also be into tissue including the muscles, brain, or eyes. Credit Wits University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.