Figure 3 (IMAGE) Shinshu University Caption Capsaicinoid biosynthesis pathways and the involvement of the 18 analyzed genes in the present study. Letters in each circle indicate the gene name and the ten co-expressed genes whose expression levels had positive correlations (P < 0.01) with capsaicinoid concentration in 'Shishito' fruits are represented by white letters in black ovals. Gray dotted lines linking between each gene indicate that strong positive correlation (r > 0.8, P < 0.001) was observed in expression levels between the two genes. PAL phenylalanine ammonia lyase, C4H cinnamate 4-hydroxylase, 4CL 4-coumaroyl-aoenzyme A ligase, HCT hydroxycinnamoyl transferase, C3H coumaroyl shikimate/quinate 3-hydroxylase, COMT caffeic acid O-methyltransferase, pAMT putative aminotransferase, BCAT branched-chain amino acid transferase, BCKDH branched-chain α-ketoacid dehydrogenase, ACL acyl carrier protein, KAS ketoacyl-ACP synthase, CaKR1 ketoacyl- ACP reductase, FAT acyl-ACP thioesterase, ACS acyl-CoA synthetase, AT3 acyltransferase 3. [modified from Arce-Rodr.guez and Ochoa-Alejo 2019; Koeda et al. 2019] Credit Copyright © 2021, Fumiya Kondo, Kenichi Matsushima et al., Shinshu University, under exclusive licence to Springer Nature Switzerland AG, part of Springer Nature Usage Restrictions The image may only be used with appropriate caption or credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.