Peptoid-Coated DNA Origami Team (IMAGE)
Caption
(Left to right) James Byrnes, Christine Wang, and Oleg Gang at Brookhaven Lab's Center for Functional Nanomaterials. Here, they used transmission electron microscopes to image 3-D DNA nanostructures (shown on the computer screen). Through these imaging studies and other experiments, they observed that the structure of these "DNA origami" remained intact after being coated with specifically designed molecules called peptoids and placed in various types of physiological conditions (e.g., solutions containing enzymes) relevant to biomedical applications. In follow-on demonstrations conducted in collaboration with Stanford University, they explored how their "peptoid-coated DNA origami" could be used for anti-cancer drug delivery.
Credit
Brookhaven National Laboratory
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