The Crystal Structure and Function of the P2Y12 Receptor (IMAGE)

University of Bonn

The Crystal Structure and Function of the P2Y12 Receptor

Caption

The receptor structure is shown as a yellow ribbon (bottom). The physiological ligand (ADP, top right-hand side) that stimulates the formation of blood clots, and the drug that suppresses platelet aggregation (AZD1283, top, left-hand side) are shown as coloured molecular stick models within a capsule (AZD1283), or on a blood coagulation thrombus (ADP), respectively.

Credit

(c) Graphic: Katya Kadyshevskaya/Stevens Laboratory/The Scripps Research Institute

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