Imaging dendritic spines (IMAGE) Optica Caption Researchers developed a 3D-2PE-STED system that can image dendritic spines deep inside the brain of a living mouse. Their system showed subtle changes that occurred between day 1 and 3 (left images). These changes are hard to distinguish using two-photon microscopy alone (right). Credit Joerg Bewersdorf, Yale School of Medicine Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.