Blocking SARS-CoV-2 cell entry (IMAGE)

Deutsches Primatenzentrum (DPZ)/German Primate Center

Blocking SARS-CoV-2 cell entry

Caption

The attachment protein "spike" of the new coronavirus SARS-CoV-2 uses the same cellular attachment factor (ACE2) as SARS-CoV and uses the cellular protease TMPRSS2 for its activation. Existing, clinically approved drugs directed against TMPRSS2 inhibit SARS-CoV-2 infection of lung cells.

Credit

Illustration: Markus Hoffmann

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Only for use in context with the press release of the German Primate Center. Please credit the author as mentioned above.

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