Figure 2 (IMAGE) RIKEN Caption Diagram of the Ccl2 and leukemia inhibitory factor (LIF) signal pathways integrating into the transcription network. Known LIF signal pathway is shown with black arrow. Our finding of Ccl2 signal pathway for promoting pluripotency is shown as dot black arrow. Abbreviations: IL-6R, interleukin-6 receptor; LIF, leukemia inhibitory factor; LIFR, leukemia inhibitory factor receptor; NC, negative control; PI(3)K, phosphoinositide 3-kinase. Credit RIKEN Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.