Lung Tumors (IMAGE) Salk Institute Caption Image of lung cancer shows normal lung (light purple) and tumors (dark purple). Inactivation of SIK1 and SIK3 leads to tumor growth and inflammation, revealing for the first time that SIK kinases mediate key functions of LKB1 in preventing lung cancer. Credit Salk Institute Usage Restrictions with credit and related coverage. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.