Reconfigurable Multi-Organ-on-a-Chip System Reliably Evaluates Chemotherapy Toxicity (2 of 5) (IMAGE)

American Association for the Advancement of Science (AAAS)

Reconfigurable Multi-Organ-on-a-Chip System Reliably Evaluates Chemotherapy Toxicity (2 of 5)

Caption

Hesperos's platform for measuring cardiac electrical activity (similar to an EKG) in the reconfigurable body-on-a-chip system. A custom compact measurement system for measuring the electrical activity of cardiac tissues fits entirely on a small desk or table. The reconfigurable body-on-a-chip system shown in the lower left (outside of the measurement platform) is placed in the heated stage (lower right, shown with a body-on-a-chip system in place) and connected to the measurement system and to a standard computer. Users can see real-time data on the screen during measurements, similar to watching an EKG monitor. This material relates to a paper that appeared in the Jun. 19, 2019, issue of <i>Science Translational Medicine</i>, published by AAAS. The paper, by C.W. McAleer at Hesperos Inc. in Orlando, FL; and colleagues was titled, "Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics."

Credit

[Credit: Hesperos]

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