Sciatic nerves from 3-month-old mice in cross section: (IMAGE)

Forschungsverbund Berlin

Sciatic nerves from 3-month-old mice in cross section:

Caption

In contrast to control animals (on the far left), animals with loss of the Rab35 protein in Schwann cells exhibit demyelination of nerve fibers: myelin outfoldings (yellow arrow); myelin degeneration (green arrow); 'tomacula' - focal thickening of the myelin sheath (red star).

Credit

Alessandra Bolino, IRCCS Ospedale San Raffaele

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