Respiratory Function (IMAGE)
Caption
LEFT: DsbA-L T/T genotype carriers are considered to have low DsbA-L expression levels which may contribute to their significantly lower respiratory function than G/G and G/T genotype carriers.
RIGHT: There is a positive correlation between the activation of adiponectin, one function of DsbA-L, and respiratory function. Since previous studies showed that differences in DsbA-L gene types are associated with reduced adiponectin activation, this study indicates that differences in the function of DsbA-L genes affect lung function decline.
Credit
Assoc. Prof. Tsuyoshi Shuto and Assist. Prof. Kentaro Oniki
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<p>Adapted from figs. 1 (mid) and 2 (right) of Oniki, K., Nohara, H., Nakashima, R., Obata, Y., Muto, N., Sakamoto, Y., ... Saruwatari, J. (2020). The DsbA-L gene is associated with respiratory function of the elderly via its adiponectin multimeric or antioxidant properties. Scientific Reports. doi:10.1038/s41598-020-62872-5 and edited to add color, arrows, and format text.</p> <p>This image is made available under the terms of <a href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0 International License</a>. Any further distribution of this work must follow the terms of this license.</p>
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