Immunosignature Profiling (IMAGE) Arizona State University Caption In immunosignaturing, a chemical marker causes the antigen-antibody pair to fluoresce, with the magnitude of fluorescence indicating the strength of antigen-antibody binding (red is strong binding, blue is weak). A single drop of blood, containing an individual's complete set of antibodies, is spread across an array of 10,000 random sequence peptides, imprinted on a microarray slide, revealing the immune system's complete pattern of activity after exposure to a pathogen, a vaccine or any other factor provoking a change in the antibody portrait. Credit The Biodesign Institute at Arizona State University Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.