Generational Inheritance of DNA Methylation (IMAGE)

Salk Institute

Generational Inheritance of DNA Methylation

Caption

Although spontaneous rates of genetic mutations are well understood, the rates of epigenetic variation in DNA methylation have remained a mystery until now. Using the plant Arabidopsis thaliana (depicted in the center), generational variation in DNA methylation was identified in five lineages separated by 30 generations of growth as indicated by the methylated pink Cs and the unmethylated green Cs.

Credit

Robert Schmitz, Joseph R. Ecker, Salk Institute for Biological Studies

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