Developmental Increase in P2Y6R Abundance Enhances Angiotensin II-Induced Hypertrophic Response (IMAGE)

National Institutes of Natural Sciences

Developmental Increase in P2Y6R Abundance Enhances Angiotensin II-Induced Hypertrophic Response

Caption

P2Y6R abundance was developmentally increased in vascular smooth muscle cells. In neonatal cells, angiotensin II induced proliferation through AT1R monomer, whereas angiotensin II induced hypertrophy of adult vascular smooth muscle cells through AT1R-P2Y6R heterodimer.

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NINS/NIPS

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