LRRK2 structure (IMAGE)

University of California - San Diego

LRRK2 structure

Caption

The molecular structure of a Parkinson's disease mutant LRRK2 was captured inside cells using advanced cryo-electron tomography and computational modeling techniques. Here, a window into a human cell carrying an LRRK2 mutation is shown in grayscale in the background. By zooming in, the structure of this important drug target was revealed (gray) decorating molecular highways called microtubules (green).

Credit

Villa Lab, UC San Diego

Usage Restrictions

Must be used in conjunction with ASAP Parkinson's research grant to UC San Diego.

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