Satellite cells are activated by components leaking from damaged muscle fibers (IMAGE)

Kumamoto University

Satellite cells are activated by components leaking from damaged muscle fibers

Caption

<p>Single myofibers were isolated from mouse muscle tissue in a suspension cell culture. Satellite cells on the myofiber were exposed to components leaking from damaged myofibers for 72 hours by co-culture with physically damaged myofibers using a glass pipette (co-culture). The percentage of activated satellite cells in the co-culture group increased compared to the no co-culture group, suggesting that satellite cells were activated by DMDFs. </p> <p>PAX7: satellite cell marker; MYOD: activation marker; *p < 0.05 </p>

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Associate Professor Yusuke Ono

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