Decision-making in Aged and Young Mice (IMAGE)
Caption
Mice were trained to do two actions (A1 and A2) in order to obtain two differently-flavoured food outcomes (O1, grain-based pellets; and O2, sweetened pellets). Then, mice were given unrestricted access to one of the pellets (specific satiety) and, immediately after, were allowed to choose between the two actions. After that, the action-outcome relationships were inverted (reversal), and the same procedure was repeated. Aged mice were able to appropriately choose the non-sated outcome on the first round, but were confused on their choice after the reversal.
Credit
Matamales and Skrbis <i>et al</i>./<i>Neuron</i> 2016
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