Hutchinson-Gilford Progeria Syndrome (IMAGE)

Singapore-MIT Alliance for Research and Technology (SMART)

Hutchinson-Gilford Progeria Syndrome

Caption

Hutchinson-Gilford Progeria Syndrome. HGPS is a childhood disorder caused by mutations in one of the major architectural proteins of the cell nucleus. In HGPS patients, the cell nucleus has dramatically aberrant morphology (bottom, right) rather than the uniform shape typically found in healthy individuals (top, right).

Credit

Source: Wikicommons, The Cell Nucleus and Aging: Tantalizing Clues and Hopeful Promises. Scaffidi P, Gordon L, Misteli T. <em>PLoS Biology</em> Vol. 3/11/2005, e395 doi:10.1371/journal.pbio.0030395

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