Figure 3. Multipoint Measurements of External K+ Concentration in Freely Moving Mice (IMAGE)
Caption
a, Experimental scheme for simultaneous electroencephalography (EEG) recording and K+ sensing in three different brain regions (hippocampus, amygdala, and cortex) of the epileptic mouse. b, c, Upon electrical stimulation of the hippocampus that resulted in different degrees of epileptic seizures, both the EEG recording and the nanosensor data show responses in amygdala and cortex. d, e, Graphs showing the seizure stage-dependent changes in the amplitude (d) and duration (e) of the nanosensor fluorescence signal in the three different locations of the mouse brain.
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