De-escalation of Conflict (IMAGE) Arizona State University Caption De-escalation of conflict can reduce costs associated with conflict to both host and microbiota. Host immune tolerance may have evolved as a strategy of managing conflict between host and microbiome, reducing costly host inflammation and microbiota virulence in the microbiome. Credit Jason Drees for the Biodesign Institute Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.