Schematic Illustration (IMAGE) Kanazawa University Caption Schematic illustration of the p53 mutation and metastasis. Combination of loss of wild-type p53 and GOF p53 mutation promotes metastasis through acquisition of stem cell property and activation of inflammatory and growth factor pathways. Credit Kanazawa University Usage Restrictions The image may only be used with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.