Sarcomere organization at molecular level. (IMAGE)

Max Planck Institute of Molecular Physiology

Sarcomere organization at molecular level.

Caption

Row 1 shows a schematic representation of the sarcomere. Row 2 shows the three-dimensional sarcomere organization and plasticity at the molecular level (filaments: pink and green, ?-Actinin: blue). Row 3: Interaction of muscle proteins in detail. First two bubbles show the interaction of the myosin heads (yellow, orange, red) with actin (green). Third bubble shows details of actin, tropomyosin and troponin in the A-band. Last bubble depicts irregular mesh of ?-Actinin (blue) cross-linking actin filaments (green, pink) in the Z-disc.

Credit

@MPI of Molecular Physiology

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