Figure 1 -- P. Vivax Life Cycle (IMAGE)

Kanazawa University

Figure 1 -- P. Vivax Life Cycle

Caption

A proportion of P. vivax sporozoites differentiate to a hypnozoite form that ultimately reactivates and proliferates leading to a blood-stage relapse. The hypnozoites are not eradicated by artemisinin and can awaken months to years after the last bout of clinical malaria, unless a drug specifically targetting the hypnozoite, primaquine, is administered. However, primaquine has severe side effects.

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Kanazawa University

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