Reduced COX Expression Associated With Hyperexcitability Of Serotonergic Neurons (IMAGE)

RIKEN

Reduced COX Expression Associated With Hyperexcitability Of Serotonergic Neurons

Caption

This is immunohistochemical and electrophysiological analysis. (top) whole mouse brain, the dotted region is the dorsal raphe where COX-negative cells were more numerous in the mutants. (botton left). Close-up of the dorsal raphe. COX-negative cells are red. (bottom right) Electrophysiological analysis showed that serotonergic neurons in the mutant dorsal raphe were more excitable than in wildtype mice.

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RIKEN National Science Institute

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