Compound Stems Damage from Brain Bleeding (1 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Compound Stems Damage from Brain Bleeding (1 of 2)

Caption

Brain hemorrhage, bleeding inside the brain caused by a ruptured blood vessel, can lead to death or disability. New research suggests that a compound that blocks oxygen-sensing enzymes in the brain improves recovery following brain hemorrhage. This material relates to a paper that appeared in the March 2, 2016, issue of Science Translational Medicine, published by AAAS. The paper, by S.S. Karuppagounder at Burke Medical Research Institute in White Plains, N.Y., and colleagues was titled, "Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models."

Credit

V. Altounian / <i>Science Translational Medicine</i> (2016)

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