Zika Virus in the Fetal Mouse Brain (IMAGE)
Caption
This visual abstract of a Cell Stem Cell study by Li, Xu, and colleagues shows that ZIKV replicates efficiently in the mouse embryonic brain by mainly targeting neural progenitor cells. They also show that infected brains are smaller with enlarged ventricles and a thinner cortex, consistent with a microcephalic phenotype.
Credit
Li, Xu, Ye, and Hong et al./Cell Stem Cell 2016
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