Disease-Causing Mutation in Motion (IMAGE)

Society for Neuroscience

Disease-Causing Mutation in Motion

Caption

Cells with a mutant form of the protein mitofusin 2 contain mitochondria that are smaller and move more slowly than those with normal proteins. This graph shows how much more normal mitochondria move over time (top graph) compared with how little mitochondria with mutated proteins travel (bottom graph).

Credit

Courtesy, with permission: Misko et al. <i>The Journal of Neuroscience</i> 2010.

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For reporters, free use with appropriate credit line. All others, please contact The Journal of Neuroscience.

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